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KMID : 0380620180500060665
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Korean Journal of Food Science and Technology
2018 Volume.50 No. 6 p.665 ~ p.670
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Physicochemical properties and biological activity of three-year-old and seven-year-old Platycodon grandiflorum extracts
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Chae Kyu-Seo
Baek Mi-Seon
Ryu Eun-Hye
Kim Ki-Deok
Kwon Ji-Wung
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Abstract
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This study was designed to evaluate the physicochemical properties and biological activities (antioxidant activity and antimicrobial activities) of three and seven-year-old Platycodon grandiflorum extracts. Three and seven-year-old Platycodon grandiflorum contained crude saponins, free amino acids and minerals. Water extracts of the three and seven-year-old plants were prepared using reflux extraction methods. The total polyphenol contents (TPC), total flavonoid contents (TFC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radical scavenging activity and antimicrobial effects of the extracts were determined. The seven-year-old Platycodon grandiflorum extract had higher TPC (5.08±0.07 TAE mg/g) and TFC (3.80±0.07 QUE mg/g). DPPH radical scavenging activity (IC50 value: 288±3.88 µg/mL) and ABTS radical scavenging activity (IC50 value: 568±2.09 µg/mL). The three and seven-year-old Platycodon grandiflorum extracts exhibited a strong antimicrobial effect against three kinds of bronchus disease-inducing bacteria; the seven-year-old Platycodon grandiflorum extracts showed a stronger antimicrobial effect than the three-year-old Platycodon grandiflorum extracts.
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KEYWORD
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antioxidant activities, antimicrobial effect, physicochemical properties, Platycodon grandiflorum
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